The Effect of Probiotics on Changes in Serum Levels of Liver Enzymes Induced by Margarine Butter in Male Wistar Rats

Background: Disorders in the burning and making of fatty acids liver under influence one or more environmental genetic stimuli lead to inflammation destruction cells. Objective: This study aimed investigate changes serum levels enzymes derived from margarine butter possible effect probiotics on this enzyme. Materials Methods: Rats were randomly divided into four groups: Negative control group receiving normal food, positive test 1 food with probiotics, 2 probiotics. In group, was given animals for weeks, intake administered simultaneously administration greasy lasting 8 then number determined by drawing blood. Results: Margarine led an increase alanine aminotransferase (ALT) alkaline phosphatase (ALP). Taking caused compensate these enzymes. The average count colonies Escherichia coli (E. coli) Clostridium consumer increased significantly compared negative prescription simultaneous compensated increase. Conclusion: general, it found that consumption along can reduce due high ALT AST. A probiotic a decreasing bacteria E. alone.